Infectious Lassa Virus, but Not Filoviruses, Is Restricted by BST-2/Tetherin

Bone marrow stromal antigen 2 (BST-2/tetherin) is a cellular membrane protein that inhibits the release of HIV-1. We show for the first time, using infectious viruses, that BST-2 also inhibits egress of arenaviruses but has no effect on filovirus replication and spread. Specifically, infectious Lass...

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Auteurs principaux: Radoshitzky, Sheli R., Dong, Lian, Chi, Xiaoli, Clester, Jeremiah C., Retterer, Cary, Spurgers, Kevin, Kuhn, Jens H., Sandwick, Sarah, Ruthel, Gordon, Kota, Krishna, Boltz, Dutch, Warren, Travis, Kranzusch, Philip J., Whelan, Sean P. J., Bavari, Sina
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2010
Sujets:
Virus-Cell Interactions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950602/
https://ncbi.nlm.nih.gov/pubmed/20686043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00103-10
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