Infectious Lassa Virus, but Not Filoviruses, Is Restricted by BST-2/Tetherin

Bone marrow stromal antigen 2 (BST-2/tetherin) is a cellular membrane protein that inhibits the release of HIV-1. We show for the first time, using infectious viruses, that BST-2 also inhibits egress of arenaviruses but has no effect on filovirus replication and spread. Specifically, infectious Lass...

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Hauptverfasser: Radoshitzky, Sheli R., Dong, Lian, Chi, Xiaoli, Clester, Jeremiah C., Retterer, Cary, Spurgers, Kevin, Kuhn, Jens H., Sandwick, Sarah, Ruthel, Gordon, Kota, Krishna, Boltz, Dutch, Warren, Travis, Kranzusch, Philip J., Whelan, Sean P. J., Bavari, Sina
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950602/
https://ncbi.nlm.nih.gov/pubmed/20686043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00103-10
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