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Mutations in the Stalk Region of the Measles Virus Hemagglutinin Inhibit Syncytium Formation but Not Virus Entry

Measles virus (MV) entry requires at least 2 viral proteins, the hemagglutinin (H) and fusion (F) proteins. We describe the rescue and characterization of a measles virus with a specific mutation in the stalk region of H (I98A) that is able to bind normally to cells but infects at a lower rate than...

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Detalhes bibliográficos
Main Authors: Ennis, Matthew K., Hu, Chunling, Naik, Shruthi K., Hallak, Louay K., Peng, Kah Whye, Russell, Stephen J., Dingli, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950563/
https://ncbi.nlm.nih.gov/pubmed/20702637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00789-10
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