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Epitope-Specific Regulatory CD4 T Cells Reduce Virus-Induced Illness while Preserving CD8 T-Cell Effector Function at the Site of Infection

The role of epitope-specific regulatory CD4 T cells in modulating CD8 T-cell-mediated immunopathology during acute viral infection has not been well defined. In the murine model of respiratory syncytial virus (RSV) infection, CD8 T cells play an important role in both viral clearance and immunopatho...

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Detalhes bibliográficos
Main Authors: Liu, Jie, Ruckwardt, Tracy J., Chen, Man, Nicewonger, John D., Johnson, Teresa R., Graham, Barney S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950556/
https://ncbi.nlm.nih.gov/pubmed/20686045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00963-10
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