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Regulatory T Cells Promote Early Influx of CD8(+) T Cells in the Lungs of Respiratory Syncytial Virus-Infected Mice and Diminish Immunodominance Disparities

In addition to regulating autoimmunity and antitumor immunity, CD4(+) CD25(+) FoxP3(+) natural regulatory T (Treg) cells are global regulators of adaptive immune responses. Depletion of these cells with the anti-CD25 antibody PC61 prior to primary respiratory syncytial virus (RSV) infection was part...

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Detalhes bibliográficos
Main Authors: Ruckwardt, Tracy J., Bonaparte, Kathryn L., Nason, Martha C., Graham, Barney S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655550/
https://ncbi.nlm.nih.gov/pubmed/19153229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00036-09
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