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Downregulation of Thrombomodulin, a Novel Target of Snail, Induces Tumorigenesis through Epithelial-Mesenchymal Transition

The expression of thrombomodulin (TM), a calcium-dependent adhesion molecule, is frequently downregulated in various cancer types. However, the mechanism responsible for the low expression level of TM in tumorigenesis is unknown. Here, an inverse expression of TM and Snail was detected in different...

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Detalhes bibliográficos
Main Authors: Kao, Yuan-Chung, Wu, Li-Wha, Shi, Chung-Sheng, Chu, Che-Hsien, Huang, Chia-Wei, Kuo, Chou-Pin, Sheu, Hamm-Ming, Shi, Guey-Yueh, Wu, Hua-Lin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950553/
https://ncbi.nlm.nih.gov/pubmed/20713448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01021-09
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