Lectin-like domain of thrombomodulin binds to its specific ligand Lewis Y antigen and neutralizes lipopolysaccharide-induced inflammatory response

Thrombomodulin (TM), a widely expressing glycoprotein originally identified in vascular endothelium, is an important cofactor in the protein C anticoagulant system. TM appears to exhibit anti-inflammatory ability through both protein C–dependent and –independent pathways. We presently have demonstra...

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Bibliografiske detaljer
Main Authors: Shi, Chung-Sheng, Shi, Guey-Yueh, Hsiao, Shi-Ming, Kao, Yuan-Chung, Kuo, Kuan-Lin, Ma, Chih-Yuan, Kuo, Cheng-Hsiang, Chang, Bi-Ing, Chang, Chuan-Fa, Lin, Chun-Hung, Wong, Chi-Huey, Wu, Hua-Lin
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2008
Fag:
Immunobiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572793/
https://ncbi.nlm.nih.gov/pubmed/18711002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-03-142760
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