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A deletion in the gene for glycoprotein IIb associated with Glanzmann's thrombasthenia.

The platelet fibrinogen receptor is composed of a complex of glycoproteins (GP) IIb and IIIa on the surface of platelets. Deficient function of this receptor prevents normal platelet aggregation, resulting in Glanzmann's thrombasthenia (GT). In this paper, we describe a black thrombasthenic pat...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Burk, C D, Newman, P J, Lyman, S, Gill, J, Coller, B S, Poncz, M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295042/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1702098/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114982
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