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A deletion in the gene for glycoprotein IIb associated with Glanzmann's thrombasthenia.

The platelet fibrinogen receptor is composed of a complex of glycoproteins (GP) IIb and IIIa on the surface of platelets. Deficient function of this receptor prevents normal platelet aggregation, resulting in Glanzmann's thrombasthenia (GT). In this paper, we describe a black thrombasthenic patient...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Burk, C D, Newman, P J, Lyman, S, Gill, J, Coller, B S, Poncz, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1991
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295042/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1702098/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114982
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