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Developmental Expression of a Trypanosoma cruzi Phosphoinositide-Specific Phospholipase C in Amastigotes and Stimulation of Host Phosphoinositide Hydrolysis

Phosphoinositide phospholipase C (PI-PLC) plays an essential role in cell signaling. A unique Trypanosoma cruzi PI-PLC (TcPI-PLC) is lipid modified in its N terminus and localizes to the outer surface of the plasma membrane of amastigotes. We show here that TcPI-PLC is developmentally regulated in a...

詳細記述

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書誌詳細
主要な著者: de Paulo Martins, Vicente, Galizzi, Melina, Salto, Maria Laura, Docampo, Roberto, Moreno, Silvia N. J.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950344/
https://ncbi.nlm.nih.gov/pubmed/20643853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00473-10
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