A Critical Role of c-Cbl-Interacting Protein of 85 kDa in the Development and Progression of Head and Neck Squamous Cell Carcinomas through the Ras-ERK Pathway

Activation of the transforming growth factor (TGF) α/epidermal growth factor receptor (EGFR)-mediated signaling pathway is a common mechanism for dysregulated growth of head and neck squamous cell carcinoma (HNSCC). c-Cbl-interacting protein of 85 kDa (CIN85) is an adaptor protein that facilitates E...

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Hauptverfasser: Wakasaki, Takahiro, Masuda, Muneyuki, Niiro, Hiroaki, Jabbarzadeh-Tabrizi, Siamak, Noda, Kumiko, Taniyama, Tadayoshi, Komune, Shizuo, Akashi, Koichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press Inc. 2010
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950328/
https://ncbi.nlm.nih.gov/pubmed/20927317
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