Ornithine Decarboxylase-1 Polymorphism, Chemoprevention With Eflornithine and Sulindac, and Outcomes Among Colorectal Adenoma Patients

The ornithine decarboxylase-1 (ODC1) polymorphism at position +316 affects binding by transcriptional activators and repressors and modulates the risk of metachronous colorectal adenomas, particularly in association with aspirin use. We investigated the effects of ODC1 after treatment with difluorom...

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Main Authors: Zell, Jason A., McLaren, Christine E., Chen, Wen-Pin, Thompson, Patricia A., Gerner, Eugene W., Meyskens, Frank L.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2010
Assuntos:
Brief Communication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950167/
https://ncbi.nlm.nih.gov/pubmed/20798393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djq325
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