The DNA/RNA-Dependent RNA Polymerase QDE-1 Generates Aberrant RNA and dsRNA for RNAi in a Process Requiring Replication Protein A and a DNA Helicase

The production of aberrant RNA (aRNA) is the initial step in several RNAi pathways. How aRNA is produced and specifically recognized by RNA-dependent RNA polymerases (RdRPs) to generate double-stranded RNA (dsRNA) is not clear. We previously showed that in the filamentous fungus Neurospora, the RdRP...

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Main Authors: Lee, Heng-Chi, Aalto, Antti P., Yang, Qiuying, Chang, Shwu-Shin, Huang, Guocun, Fisher, Daniel, Cha, Joonseok, Poranen, Minna M., Bamford, Dennis H., Liu, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950127/
https://ncbi.nlm.nih.gov/pubmed/20957187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000496
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