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A Method for Identifying Small-Molecule Aggregators Using Photonic Crystal Biosensor Microplates
Small molecules identified through high-throughput screens are an essential element in pharmaceutical discovery programs. It is now recognized that a substantial fraction of small molecules exhibit aggregating behavior leading to false positive results in many screening assays, typically due to nons...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2950101/ https://ncbi.nlm.nih.gov/pubmed/20930952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jala.2009.06.008 |
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