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A General Method for Discovering Inhibitors of Protein–DNA Interactions Using Photonic Crystal Biosensors

Protein–DNA interactions are essential for fundamental cellular processes such as transcription, DNA damage repair, and apoptosis. As such, small molecule disruptors of these interactions could be powerful tools for investigation of these biological processes, and such compounds would have great pot...

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Detalhes bibliográficos
Main Authors: Chan, Leo L., Pineda, Maria, Heeres, James T., Hergenrother, Paul J., Cunningham, Brian T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805019/
https://ncbi.nlm.nih.gov/pubmed/18582039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb800057j
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