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RIN1 is a Breast Tumor Suppressor Gene

Breast cancer progression is driven by altered gene expression. We show that the RIN1 gene, which encodes a RAS effector regulating epithelial cell properties, is silenced in breast tumor cell lines compared to cultured human mammary epithelial cells. We also report that RIN1 is often reduced in hum...

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Detalhes bibliográficos
Main Authors: Milstein, Marc, Mooser, Chelsea K., Hu, Hailiang, Fejzo, Marlena, Slamon, Dennis, Goodglick, Lee, Dry, Sarah, Colicelli, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950063/
https://ncbi.nlm.nih.gov/pubmed/18089779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-1147
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