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Identification of Fat4 as a candidate tumor suppressor gene in breast cancers

Fat, a candidate tumor suppressor in drosophila, is a component of Hippo signaling pathway involved in controlling organ size. We found that a ~3Mbp deletion in mouse chromosome 3 caused tumorigenesis of a non-tumorigenic mammary epithelial cell line. The expression of Fat4 gene, one member of the F...

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Bibliografiske detaljer
Main Authors: Qi, Chao, Zhu, Yiwei Tony, Hu, Liping, Zhu, Yi-Jun
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667156/
https://ncbi.nlm.nih.gov/pubmed/19048595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.23775
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