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The IL Sequence in the LLKIL Motif in CXCR2 Is Required for Full Ligand-induced Activation of Erk, Akt, and Chemotaxis in HL60 Cells
The chemotaxis of differentiated HL60 cells stably expressing CXCR2 was examined in a microfluidic gradient device where the steepness of the CXCL8 chemokine gradient was varied from 2 pg/ml/μm (0–1 ng/ml over a width of 500 μm) to 50 pg/ml/μm (0–25 ng/ml over 500 μm). The differentiated HL60 cells...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2950015/ https://ncbi.nlm.nih.gov/pubmed/16990258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M605883200 |
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