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Manipulation of Adenosine Kinase Affects Sleep Regulation in Mice

Sleep and sleep intensity are enhanced by adenosine and its receptor agonists, whereas adenosine receptor antagonists induce wakefulness. Adenosine kinase (ADK) is the primary enzyme metabolizing adenosine in adult brain. To investigate whether adenosine metabolism or clearance affects sleep, we rec...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Palchykova, Svitlana, Winsky-Sommerer, Raphaelle, Shen, Hai-Ying, Boison, Detlev, Gerling, Andrea, Tobler, Irene
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950004/
https://ncbi.nlm.nih.gov/pubmed/20881134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1359-10.2010
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