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Manipulation of Adenosine Kinase Affects Sleep Regulation in Mice

Sleep and sleep intensity are enhanced by adenosine and its receptor agonists, whereas adenosine receptor antagonists induce wakefulness. Adenosine kinase (ADK) is the primary enzyme metabolizing adenosine in adult brain. To investigate whether adenosine metabolism or clearance affects sleep, we rec...

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Detalhes bibliográficos
Main Authors: Palchykova, Svitlana, Winsky-Sommerer, Raphaelle, Shen, Hai-Ying, Boison, Detlev, Gerling, Andrea, Tobler, Irene
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950004/
https://ncbi.nlm.nih.gov/pubmed/20881134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1359-10.2010
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