Influence of methotrexate exposure on outcome in patients treated with MBVP chemotherapy for primary central nervous system lymphoma

AIMS: Although the standard treatment for primary central nervous system lymphoma (PCNSL) consists of three cycles of MBVP (methotrexate, BCNU, VP16, methylprednisolone) and radiotherapy, early failure of treatment may require modification of the treatment. However, our understanding of the outcome...

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Main Authors: Blasco, Hélène, Senecal, Delphine, Le Gouge, Amélie, Pinard, Emmanuelle, Benz-de Bretagne, Isabelle, Colombat, Philippe, Hulot, Jean-Sébastien, Chatelut, Etienne, Le Guellec, Chantal
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2010
Fag:
Pharmacokinetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949909/
https://ncbi.nlm.nih.gov/pubmed/20716237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2010.03712.x
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