Influence of methotrexate exposure on outcome in patients treated with MBVP chemotherapy for primary central nervous system lymphoma

AIMS: Although the standard treatment for primary central nervous system lymphoma (PCNSL) consists of three cycles of MBVP (methotrexate, BCNU, VP16, methylprednisolone) and radiotherapy, early failure of treatment may require modification of the treatment. However, our understanding of the outcome...

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Detalhes bibliográficos
Main Authors: Blasco, Hélène, Senecal, Delphine, Le Gouge, Amélie, Pinard, Emmanuelle, Benz-de Bretagne, Isabelle, Colombat, Philippe, Hulot, Jean-Sébastien, Chatelut, Etienne, Le Guellec, Chantal
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Pharmacokinetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949909/
https://ncbi.nlm.nih.gov/pubmed/20716237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2010.03712.x
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