Preferential expression of human Fc gamma RIIIPMN (CD16) in paroxysmal nocturnal hemoglobinuria. Discordant expression of glycosyl phosphatidylinositol-linked proteins.

The isoform of Fc gamma RIII (CD16) expressed on PMN has a GPI membrane anchor, and in paroxysmal nocturnal hemoglobinuria (PNH) there is a deficiency in Fc gamma RIII expression on PMN. Contrary to expectation, however, CD16 expression is preserved (albeit at reduced levels) in all affected PNH PMN...

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Vydáno v:	J Clin Invest
Hlavní autoři:	Edberg, J C, Salmon, J E, Whitlow, M, Kimberly, R P
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 1991
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294990/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1702101/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115001
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