Tumour stromal cells derived from paediatric malignancies display MSC-like properties and impair NK cell cytotoxicity

BACKGROUND: Tumour growth and metastatic infiltration are favoured by several components of the tumour microenvironment. Bone marrow-derived multipotent mesenchymal stromal cells (MSC) are known to contribute to the tumour stroma. When isolated from healthy bone marrow, MSC exert potent antiprolifer...

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Autori principali: Johann, Pascal-David, Vaegler, Martin, Gieseke, Friederike, Mang, Philippa, Armeanu-Ebinger, Sorin, Kluba, Torsten, Handgretinger, Rupert, Müller, Ingo
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949810/
https://ncbi.nlm.nih.gov/pubmed/20858262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-501
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