Low physiologic oxygen tensions reduce proliferation and differentiation of human multipotent mesenchymal stromal cells

BACKGROUND: Human multipotent mesenchymal stromal cells (MSC) can be isolated from various tissues including bone marrow. Here, MSC participate as bone lining cells in the formation of the hematopoietic stem cell niche. In this compartment, the oxygen tension is low and oxygen partial pressure is es...

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Detalhes bibliográficos
Main Authors: Holzwarth, Christina, Vaegler, Martin, Gieseke, Friederike, Pfister, Stefan M, Handgretinger, Rupert, Kerst, Gunter, Müller, Ingo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827377/
https://ncbi.nlm.nih.gov/pubmed/20109207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-11-11
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