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P-cadherin counteracts myosin II-B function: implications in melanoma progression

BACKGROUND: Malignant transformation of melanocytes is frequently attended by a switch in cadherin expression profile as shown for E- and N-cadherin. For P-cadherin, downregulation in metastasizing melanoma has been demonstrated, and over-expression of P-cadherin in melanoma cell lines has been show...

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Bibliografiske detaljer
Main Authors: Jacobs, Koen, Van Gele, Mireille, Forsyth, Ramses, Brochez, Lieve, Vanhoecke, Barbara, De Wever, Olivier, Bracke, Marc
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949802/
https://ncbi.nlm.nih.gov/pubmed/20860798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-255
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