Polymorphisms in folate-metabolizing genes, chromosome damage, and risk of Down syndrome in Italian women: identification of key factors using artificial neural networks

BACKGROUND: Studies in mothers of Down syndrome individuals (MDS) point to a role for polymorphisms in folate metabolic genes in increasing chromosome damage and maternal risk for a Down syndrome (DS) pregnancy, suggesting complex gene-gene interactions. This study aimed to analyze a dataset of gene...

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Detaylı Bibliyografya
Asıl Yazarlar: Coppedè, Fabio, Grossi, Enzo, Migheli, Francesca, Migliore, Lucia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2010
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949778/
https://ncbi.nlm.nih.gov/pubmed/20868477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-3-42
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