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Plasma Homocysteine and Polymorphisms of Genes Involved in Folate Metabolism Correlate with DNMT1 Gene Methylation Levels

DNA methyltransferase 1 (DNMT1) is responsible for the maintenance of DNA methylation patterns during cell division. Several human diseases are characterized by impaired DNMT1 gene methylation, but less is known about the factors that regulate DNMT1 promoter methylation levels. Dietary folates and r...

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Detalhes bibliográficos
Publicado no:Metabolites
Main Authors: Coppedè, Fabio, Stoccoro, Andrea, Tannorella, Pierpaola, Migliore, Lucia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6950100/
https://ncbi.nlm.nih.gov/pubmed/31817852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo9120298
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