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Tamoxifen enhances the cytotoxic effects of nelfinavir in breast cancer cells

INTRODUCTION: The HIV protease inhibitor nelfinavir is currently under investigation as a new anti-cancer drug. Several studies have shown that nelfinavir induces cell cycle arrest, endoplasmic reticulum stress, autophagy, and apoptosis in cancer cells. In the present article, the effect of nelfinav...

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Detalhes bibliográficos
Main Authors: Brüning, Ansgar, Friese, Klaus, Burges, Alexander, Mylonas, Ioannis
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949632/
https://ncbi.nlm.nih.gov/pubmed/20594311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2602
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