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The Proliferating Role of Insulin and Insulin-Like Growth Factors in Cancer
Epidemiological studies have reported an increased risk of cancer in those with type 2 diabetes (T2DM) and obesity, related in part to hyperinsulinemia, secondary to insulin resistance. Hyperinsulinemia leads to increased insulin-like growth factor-1 (IGF-I) expression. In fact, increased insulin, I...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2949481/ https://ncbi.nlm.nih.gov/pubmed/20663687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2010.06.007 |
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