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The Proliferating Role of Insulin and Insulin-Like Growth Factors in Cancer

Epidemiological studies have reported an increased risk of cancer in those with type 2 diabetes (T2DM) and obesity, related in part to hyperinsulinemia, secondary to insulin resistance. Hyperinsulinemia leads to increased insulin-like growth factor-1 (IGF-I) expression. In fact, increased insulin, I...

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Autors principals: Gallagher, Emily Jane, LeRoith, Derek
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949481/
https://ncbi.nlm.nih.gov/pubmed/20663687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2010.06.007
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