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The stringent response is required for full virulence of Mycobacterium tuberculosis in guinea pigs
During human latent tuberculosis (TB) infection, Mycobacterium tuberculosis likely resides within the nutrient-starved environment of caseous lung granulomas. The stringent response alarmone (p)ppGpp is synthesized by Rel in response to nutrient starvation, thus enabling tubercle bacilli to restrict...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2949470/ https://ncbi.nlm.nih.gov/pubmed/20863231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/656524 |
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