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Assessment of regional differences in tariquidar-induced P-glycoprotein modulation at the human blood–brain barrier
We attempted to assess regional differences in cerebral P-glycoprotein (P-gp) function by performing paired positron emission tomography (PET) scans with the P-gp substrate (R)-[(11)C]verapamil in five healthy subjects before and after i.v. infusion of tariquidar (2 mg/kg). Comparison of tariquidar-...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2949150/ https://ncbi.nlm.nih.gov/pubmed/20010957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2009.265 |
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