Lataa...

Mutant ubiquitin-mediated β-secretase stability via activation of caspase-3 is related to β-amyloid accumulation in ischemic striatum in rats

Previous studies have demonstrated that ischemic stroke increases β-amyloid (Aβ) production by increasing β-secretase (BACE1) through activation of caspase-3, and stimulates generation of mutant ubiquitin (UBB(+1)) in rat brains. In this study, we examined whether caspase-3 activation participates i...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Zhang, Yong, Xiong, Man, Yan, Ri-Qiang, Sun, Feng-Yan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949147/
https://ncbi.nlm.nih.gov/pubmed/19844237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2009.228
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!