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Individual Vγ2-Jγ1.2+ T cells respond to both isopentenylpyrophosphate and Daudi cell stimulation: Generating tumor effectors with low molecular weight phosphoantigens

Human Vγ2Vδ2 T cells exhibit T cell receptor-dependent, MHC-unrestricted recognition of antigen and play important roles in tumor and pathogen immunity. To characterize antigen recognition by the Vγ2Vδ2 TCR, we used the combined approach of spectratyping and CDR3 sequence analysis that measures chan...

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Bibliografiske detaljer
Main Authors: Hebbeler, Andrew M., Cairo, Cristiana, Cummings, Jean-Saville, Pauza, C. David
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948954/
https://ncbi.nlm.nih.gov/pubmed/17131122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-006-0235-6
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