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Individual Vγ2-Jγ1.2+ T cells respond to both isopentenylpyrophosphate and Daudi cell stimulation: Generating tumor effectors with low molecular weight phosphoantigens

Human Vγ2Vδ2 T cells exhibit T cell receptor-dependent, MHC-unrestricted recognition of antigen and play important roles in tumor and pathogen immunity. To characterize antigen recognition by the Vγ2Vδ2 TCR, we used the combined approach of spectratyping and CDR3 sequence analysis that measures chan...

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Autors principals: Hebbeler, Andrew M., Cairo, Cristiana, Cummings, Jean-Saville, Pauza, C. David
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948954/
https://ncbi.nlm.nih.gov/pubmed/17131122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-006-0235-6
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