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Defective GABAergic Neurotransmission and Pharmacological Rescue of Neuronal Hyperexcitability in the Amygdala in a Mouse Model of Fragile X Syndrome

Fragile X syndrome (FXS) is a neurodevelopmental disorder characterized by variable cognitive impairment and behavioral disturbances such as exaggerated fear, anxiety and gaze avoidance. Consistent with this, findings from human brain imaging studies suggest dysfunction of the amygdala. Underlying a...

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Bibliografiska uppgifter
Huvudupphovsmän: Olmos-Serrano, Jose Luis, Paluszkiewicz, Scott M., Martin, Brandon S., Kaufmann, Walter E., Corbin, Joshua G., Huntsman, Molly M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948869/
https://ncbi.nlm.nih.gov/pubmed/20660275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1714-10.2010
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