Defective GABAergic Neurotransmission and Pharmacological Rescue of Neuronal Hyperexcitability in the Amygdala in a Mouse Model of Fragile X Syndrome

Fragile X syndrome (FXS) is a neurodevelopmental disorder characterized by variable cognitive impairment and behavioral disturbances such as exaggerated fear, anxiety and gaze avoidance. Consistent with this, findings from human brain imaging studies suggest dysfunction of the amygdala. Underlying a...

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Autores principales: Olmos-Serrano, Jose Luis, Paluszkiewicz, Scott M., Martin, Brandon S., Kaufmann, Walter E., Corbin, Joshua G., Huntsman, Molly M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2010
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948869/
https://ncbi.nlm.nih.gov/pubmed/20660275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1714-10.2010
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