Water-Mediated Catalyst Preactivation: An Efficient Protocol for C-N Cross-Coupling Reactions

[Image: see text] A protocol for forming a highly active Pd(0) catalyst from Pd(OAc)(2), water, and biaryldialkylphosphine ligands has been developed. This protocol generates a catalyst system, which exhibits excellent reactivity and efficiency in the coupling of a variety of amides and anilines wit...

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Bibliographic Details
Main Authors: Fors, Brett P., Krattiger, Philipp, Strieter, Eric, Buchwald, Stephen L.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948866/
https://ncbi.nlm.nih.gov/pubmed/18620415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol801285g
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