Comparative analysis of promoter methylation and gene expression endpoints between tumorous and non-tumorous tissues from HCV-positive patients with hepatocellular carcinoma

Transcriptional silencing of tumor suppressor genes and other cancer-related genes induced by promoter CpG island hypermethylation is an important epigenetic mechanism of hepatocarcinogenesis. Previous studies have established methylation profiles of hepatocellular carcinomas (HCCs) and demonstrated...

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Hauptverfasser: Formeister, Eric J., Tsuchiya, Masato, Fujii, Hideki, Shpyleva, Svitlana, Pogribny, Igor P., Rusyn, Ivan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948626/
https://ncbi.nlm.nih.gov/pubmed/20736025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2010.07.013
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