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The DEN and CCl(4)-induced Mouse Model of Fibrosis and Inflammation-associated Hepatocellular Carcinoma

Human hepatocellular carcinoma (HCC) mostly develops as a complication of fibrosis or cirrhosis. While most human studies of HCC provide crucial insights into the molecular signatures of HCC, seldom they address the etiology of HCC. Mouse models are essential tools for investigating pathogenesis of...

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Main Authors: Uehara, Takeki, Pogribny, Igor P., Rusyn, Ivan
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4214366/
https://ncbi.nlm.nih.gov/pubmed/25181010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471141755.ph1430s66
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