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The DEN and CCl(4)-induced Mouse Model of Fibrosis and Inflammation-associated Hepatocellular Carcinoma

Human hepatocellular carcinoma (HCC) mostly develops as a complication of fibrosis or cirrhosis. While most human studies of HCC provide crucial insights into the molecular signatures of HCC, seldom they address the etiology of HCC. Mouse models are essential tools for investigating pathogenesis of...

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Detalhes bibliográficos
Main Authors: Uehara, Takeki, Pogribny, Igor P., Rusyn, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4214366/
https://ncbi.nlm.nih.gov/pubmed/25181010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471141755.ph1430s66
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