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Translation initiation on mammalian mRNAs with structured 5′-UTRs requires DExH-box protein DHX29
Eukaryotic protein synthesis begins with assembly of 48S initiation complexes at the initiation codon of mRNA, which requires at least 7 initiation factors (eIFs). First, 43S preinitiation complexes comprising 40S ribosomal subunits, eIFs 3, 2, 1, 1A and tRNA(Met)(i) attach to the 5′-proximal region...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2948571/ https://ncbi.nlm.nih.gov/pubmed/19109895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.10.037 |
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