Translation initiation on mammalian mRNAs with structured 5′-UTRs requires DExH-box protein DHX29

Eukaryotic protein synthesis begins with assembly of 48S initiation complexes at the initiation codon of mRNA, which requires at least 7 initiation factors (eIFs). First, 43S preinitiation complexes comprising 40S ribosomal subunits, eIFs 3, 2, 1, 1A and tRNA(Met)(i) attach to the 5′-proximal region...

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Detaylı Bibliyografya
Asıl Yazarlar: Pisareva, Vera P., Pisarev, Andrey V., Komar, Anton A., Hellen, Christopher U. T., Pestova, Tatyana V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948571/
https://ncbi.nlm.nih.gov/pubmed/19109895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.10.037
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