Nuclear localisation and epigenetic inactivation of the ras effector/tumour suppressor RASSF2A in multiple human cancers

RASSF2 is a recently identified member of a class of novel tumour suppressor genes, all containing a ras association domain. We previously demonstrated that the A isoform of RASSF2, is frequently inactivated by promoter region hypermethylation in colorectal tumours and adenomas, methylation was tumo...

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Autores principales: Cooper, Wendy N., Dickinson, Rachel E., Dallol, Ashraf, Grigorieva, Elvira V., Pavlova, Tatiana V., Hesson, Luke B., Bieche, Ivan, Broggini, Massimo, Maher, Eamonn R, Zabarovsky, Eugene R., Clark, Geoffrey J, Latif, Farida
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948550/
https://ncbi.nlm.nih.gov/pubmed/17891178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210805
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