Human β-defensin 3 has immunosuppressive activity in vitro and in vivo

β-defensins are antimicrobial peptides with an essential role in the innate immune response. In addition β-defensins can also chemoattract cells involved in adaptive immunity. Until now, based on evidence from dendritic cell stimulation, human β defensin-3 (hBD3) was considered pro-inflammatory. We...

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Autori principali: Semple, Fiona, Webb, Sheila, Li, Hsin-Ni, Patel, Hetal B, Perretti, Mauro, Jackson, Ian J, Gray, Mohini, Davidson, Donald J, Dorin, Julia R
Natura: Artigo
Lingua:Inglês
Pubblicazione: WILEY-VCH Verlag 2010
Soggetti:
Immunomodulation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948537/
https://ncbi.nlm.nih.gov/pubmed/20104491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200940041
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