The inhibitor of cyclin-dependent kinases, olomoucine II, exhibits potent antiviral properties

BACKGROUND: Olomoucine II, the most recent derivative of roscovitine, is an exceptionally potent pharmacological inhibitor of cyclin-dependent kinase activities. Here, we report that olomoucine II is also an effective antiviral agent. METHODS: Antiviral activities of olomoucine II were tested on a r...

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Detalhes bibliográficos
Main Authors: Holcakova, Jitka, Tomasec, Peter, Bugert, Joachim J, Wang, Eddie CY, Wilkinson, Gavin WG, Hrstka, Roman, Krystof, Vladimir, Strnad, Miroslav, Vojtesek, Borivoj
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948526/
https://ncbi.nlm.nih.gov/pubmed/20054100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP1460
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