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PP2A Mediated AMPK Inhibition Promotes HSP70 Expression in Heat Shock Response

BACKGROUND: Under stress, AMP-activated protein kinase (AMPK) plays a central role in energy balance, and the heat shock response is a protective mechanism for cell survival. The relationship between AMPK activity and heat shock protein (HSP) expression under stress is unclear. METHODOLOGY/PRINCIPAL...

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Detalhes bibliográficos
Main Authors: Wang, Ting, Yu, Qiujing, Chen, Juan, Deng, Bo, Qian, Lihua, Le, Yingying
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948495/
https://ncbi.nlm.nih.gov/pubmed/20957029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013096
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