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Mathematical Modeling of the Eukaryotic Heat-Shock Response: Dynamics of the hsp70 Promoter

The heat-shock response in humans and other eukaryotes is a highly conserved genetic network that coordinates the cellular response to protein damage and is essential for adaptation and survival of the stressed cell. It involves an immediate and transient activation of heat-shock transcription facto...

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Bibliographic Details
Main Authors: Rieger, Theodore R., Morimoto, Richard I., Hatzimanikatis, Vassily
Format: Artigo
Language:Inglês
Published: Biophysical Society 2005
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305221/
https://ncbi.nlm.nih.gov/pubmed/15626701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.055301
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