Ticagrelor: The First Reversibly Binding Oral P2Y(12) Receptor Antagonist

Ticagrelor (AZD6140) is the first reversibly binding oral P2Y(12) receptor antagonist that blocks ADP-induced platelet aggregation. Unlike thienopyridines, which irreversibly bind to the P2Y(12) receptor for the lifetime of the platelet, ticagrelor binds reversibly to the receptor and exhibits rapid...

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Hlavní autoři: Husted, Steen, van Giezen, JJJ
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948430/
https://ncbi.nlm.nih.gov/pubmed/19604248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-5922.2009.00096.x
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