Evidence that herpes simplex virus DNA derived from quiescently infected cells in vitro, and latently infected cells in vivo, is physically damaged

Using PCR and alkaline gel electrophoresis, we show that, compared with DNA derived from virions used to establish infection, herpes simplex virus DNA derived from quiescently infected rat pheochromocytoma (PC12) cells in culture accumulates alkaline-labile lesions. That is, compared with equivalent...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Millhouse, Scott, Su, Ying-Hsiu, Zhang, Xianchao, Wang, Xiaohe, Song, Benjamin P., Zhu, Li, Oppenheim, Emily, Fraser, Nigel W., Block, Timothy M.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948418/
https://ncbi.nlm.nih.gov/pubmed/20874012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/13550284.2010.515651
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares