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Dysfunction of the Ca(V)2.1 calcium channel in cerebellar ataxias
Mutations in the CACNA1A gene are associated with episodic ataxia type 2 (EA2) and spinocerebellar ataxia type 6 (SCA6). CACNA1A encodes the α-subunit of the P/Q-type calcium channel or Ca(V)2.1, which is highly enriched in the cerebellum. It is one of the main channels linked to synaptic transmissi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biology Reports
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2948357/ https://ncbi.nlm.nih.gov/pubmed/20948794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3410/B2-4 |
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